Home / People / / Wenyuan Gao

Wenyuan Gao——Professor

Nationality:
CHINA
Phone:
022-87401895
Email:
pharmgao@tju.edu.cn
Office:
Room A502, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
1994 Ph. D. Peking Union Medical College, China
Professional Experience
1994-1998 Assistant and Associate professor Chinese Academy of Medical Sciences and Peking Union Medical College, China
1998-2000 Postdoctoral fellow Chungbuk National University, Korea
2000-2001 Hong Kong Institute of Biotechnology LTD, Hong Kong
2002-2015 Professor Tianjin University, China
Research Area

The research of the Gao group encompasses three main areas, including 1) Production of active constituents by biotechnology in medicinal plants, b) Development of functional products from Traditional Chinese Medicine and natural products, and c) Development of new drugs from Traditional Chinese Medicine and natural products.

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Honors and Awards
Patents
Highlighted Publications
Man Shuli., Yang Li., Xiang Hao., Lu Guanyu., Wang Yijia., Liu Changxiao., Gao Wenyuan.(2020). Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats. Biomed Pharmacother, 125(undefined), 109977. doi:10.1016/j.biopha.2020.109977
Meng Xin., Dong Honghong., Pan Yiwu., Ma Long., Liu Changxiao., Man Shuli., Gao Wenyuan.(2019). Diosgenyl Saponin Inducing Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptotic Pathways in Liver Cancer Cells. J Agric Food Chem, 67(41), 11428-11435. doi:10.1021/acs.jafc.9b05131
Cui Jingxia., Man Shuli., Cui Nina., Yang Li., Guo Qianbei., Ma Long., Gao Wenyuan.(2019). The synergistic anticancer effect of formosanin C and polyphyllin VII based on caspase-mediated cleavage of Beclin1 inhibiting autophagy and promoting apoptosis. Cell Prolif, 52(1), e12520. doi:10.1111/cpr.12520
Man Shuli., Zhang Lili., Cui Jingxia., Yang Li., Ma Long., Gao Wenyuan.(2018). Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells. Cell Prolif, 51(4), e12458. doi:10.1111/cpr.12458
Qu Zhuo., Zhang Jingze., Yang Honggai., Gao Jing., Chen Hong., Liu Changxiao., Gao Wenyuan.(2017). Prunella vulgaris L., an Edible and Medicinal Plant, Attenuates Scopolamine-Induced Memory Impairment in Rats. J Agric Food Chem, 65(2), 291-300. doi:10.1021/acs.jafc.6b04597
ResearcherID Publications
Year Title Author(s) Source Volume
2015 Use of partial least-squares discriminant analysis to study the effects of gradual scale-up of culture, and optimization of bioreactor angle and aeration volume on culture of Panax quinquefolium L. adventitious roots in a 5-L balloon-type bubble bioreacto Wang, Qin; Wang, Juan; Li, Jing; et al. Research on Chemical Intermediates 41
2015 Study on The Relationship Between Chemical Compositions and Antioxidative Activity of Ziziphus Jujuba Mill. by Chemometric Approach Zhang, Zhidan; Gao, Wenyuan; Yan, Yanan; et al. International Journal of Food Properties 18
2015 The influence of compatibility of processed radix Aconiti Kusnezoffii on the pharmacokinetic of four components in Glycyrrhiza uralensis Fisch Zhou, Bin; Zhang, Jingze; Wu, Shanshan; et al. Journal of Ethnopharmacology 169
2015 Role of Effective Composition on Antioxidant, Anti-inflammatory, Sedative-Hypnotic Capacities of 6 Common Edible Lilium Varieties Wang, Tingting; Huang, Hanhan; Zhang, Yao; et al. Journal of Food Science 80
2015 Inhibition of pulmonary adenoma in diethylnitrosamine-induced rats by Rhizoma paridis saponins Man, Shuli; Li, Jing; Fan, Wei; et al. Journal of Steroid Biochemistry and Molecular Biology 154
2015 Optimization of balloon-type bubble bioreactor angle and methyl jasmonate concentration to enhance metabolite production in adventitious roots of Pseudostellaria heterophylla Wang, Qin; Wang, Juan; Chai, Hongyan; et al. Research on Chemical Intermediates 41
2015 Influence of step-wise aeration treatment on biomass and bioactive compounds of Panax ginseng adventitious root in balloon-type bubble bioreactor Wang, Juan; Gao, Wenyuan; Wang, Qin; et al. Research on Chemical Intermediates 41
2016 Preparation, physico-chemical characterization and biological activities of two modified starches from yam (Dioscorea Opposita Thunb.) Huang, Hanhan; Jiang, Qianqian; Chen, Yuling; et al. Food Hydrocolloids 55
2016 Protective effect of tetrahydropalmatine against d-galactose induced memory impairment in rat. Qu, Zhuo; Zhang, Jingze; Yang, Honggai; et al. Physiology & behavior 154
2015 Anti-diabetic activity in type 2 diabetic mice and alpha-glucosidase inhibitory, antioxidant and anti-inflammatory potential of chemically profiled pear peel and pulp extracts (Pyrus spp.) Wang, Tingting; Li, Xia; Zhou, Bin; et al. Journal of Functional Foods 13