Home / People / / Wenyuan Gao

Wenyuan Gao——Professor

Nationality:
CHINA
Phone:
022-87401895
Email:
pharmgao@tju.edu.cn
Office:
Room A502, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
1994 Ph. D. Peking Union Medical College, China
Professional Experience
1994-1998 Assistant and Associate professor Chinese Academy of Medical Sciences and Peking Union Medical College, China
1998-2000 Postdoctoral fellow Chungbuk National University, Korea
2000-2001 Hong Kong Institute of Biotechnology LTD, Hong Kong
2002-2015 Professor Tianjin University, China
Research Area

The research of the Gao group encompasses three main areas, including 1) Production of active constituents by biotechnology in medicinal plants, b) Development of functional products from Traditional Chinese Medicine and natural products, and c) Development of new drugs from Traditional Chinese Medicine and natural products.

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Honors and Awards
Patents
Highlighted Publications
Man Shuli., Yang Li., Xiang Hao., Lu Guanyu., Wang Yijia., Liu Changxiao., Gao Wenyuan.(2020). Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats. Biomed Pharmacother, 125(undefined), 109977. doi:10.1016/j.biopha.2020.109977
Meng Xin., Dong Honghong., Pan Yiwu., Ma Long., Liu Changxiao., Man Shuli., Gao Wenyuan.(2019). Diosgenyl Saponin Inducing Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptotic Pathways in Liver Cancer Cells. J Agric Food Chem, 67(41), 11428-11435. doi:10.1021/acs.jafc.9b05131
Cui Jingxia., Man Shuli., Cui Nina., Yang Li., Guo Qianbei., Ma Long., Gao Wenyuan.(2019). The synergistic anticancer effect of formosanin C and polyphyllin VII based on caspase-mediated cleavage of Beclin1 inhibiting autophagy and promoting apoptosis. Cell Prolif, 52(1), e12520. doi:10.1111/cpr.12520
Man Shuli., Zhang Lili., Cui Jingxia., Yang Li., Ma Long., Gao Wenyuan.(2018). Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells. Cell Prolif, 51(4), e12458. doi:10.1111/cpr.12458
Qu Zhuo., Zhang Jingze., Yang Honggai., Gao Jing., Chen Hong., Liu Changxiao., Gao Wenyuan.(2017). Prunella vulgaris L., an Edible and Medicinal Plant, Attenuates Scopolamine-Induced Memory Impairment in Rats. J Agric Food Chem, 65(2), 291-300. doi:10.1021/acs.jafc.6b04597
ResearcherID Publications
Year Title Author(s) Source Volume
2013 Identification and Simultaneous Determination of Twelve Active Components in the Methanol Extract of Traditional Medicine Weichang'an Pill by HPLC-DAD-ESI-MS/MS Zhang, Jingze; Gao, Wenyuan; Liu, Zhen; et al. Iranian Journal of Pharmaceutical Research 12
2013 Identification of metabolic profiling of cell culture of licorice compared with its native one Man, Shuli; Guo, Songbo; Gao, Wenyuan; et al. Analytical and Bioanalytical Chemistry 405
2013 Formulation and in vitro absorption analysis of Rhizoma paridis steroidal saponins Liu, Zhen; Wang, Jieyin; Gao, Wenyuan; et al. International Journal of Pharmaceutics 441
2013 Establishment and Quality Assessment of Tissue Cultures in Glycyrrhiza uralensis Fisch. Wang, Juan; Gao, Wenyuan; Zhang, Liming; et al. Applied Biochemistry and Biotechnology 169
2013 Effects of dynamic changes of nutrients on adventitious roots growth and periplocin accumulation in culture of Periploca sepium Bunge Yin, Shuangshuang; Gao, Wenyuan; Wang, Juan; et al. Acta Physiologiae Plantarum 35
2013 Effect of methyl jasmonate on the ginsenoside content of Panax ginseng adventitious root cultures and on the genes involved in triterpene biosynthesis Wang, Juan; Gao, Wenyuan; Zuo, Beimei; et al. Research on Chemical Intermediates 39
2013 Effect of bioreactor angle and aeration rate on growth and hydromechanics parameters in bioreactor culture of ginseng suspension cells Dong, Yanyan; Gao, Wen-Yuan; Man, Shuli; et al. Acta Physiologiae Plantarum 35
2013 Curcuma increasing antitumor effect of Rhizoma paridis saponins through absorptive enhancement of paridis saponins Man, Shuli; Li, Yuanyuan; Fan, Wei; et al. International Journal of Pharmaceutics 454
2013 Correlation among cytotoxicity, hemolytic activity and the composition of steroidal saponins from Paris L. Liu, Zhen; Gao, Wenyuan; Jing, Songsong; et al. Journal of Ethnopharmacology 149
2013 Comparison of ginsenoside composition in native roots and cultured callus cells of Panax quinquefolium L. Wang, Juan; Liu, Hui; Gao, Wen-Yuan; et al. Acta Physiologiae Plantarum 35