Home / People / / Wenyuan Gao

Wenyuan Gao——Professor

Nationality:
CHINA
Phone:
022-87401895
Email:
pharmgao@tju.edu.cn
Office:
Room A502, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
1994 Ph. D. Peking Union Medical College, China
Professional Experience
1994-1998 Assistant and Associate professor Chinese Academy of Medical Sciences and Peking Union Medical College, China
1998-2000 Postdoctoral fellow Chungbuk National University, Korea
2000-2001 Hong Kong Institute of Biotechnology LTD, Hong Kong
2002-2015 Professor Tianjin University, China
Research Area

The research of the Gao group encompasses three main areas, including 1) Production of active constituents by biotechnology in medicinal plants, b) Development of functional products from Traditional Chinese Medicine and natural products, and c) Development of new drugs from Traditional Chinese Medicine and natural products.

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Honors and Awards
Patents
Highlighted Publications
Man Shuli., Yang Li., Xiang Hao., Lu Guanyu., Wang Yijia., Liu Changxiao., Gao Wenyuan.(2020). Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats. Biomed Pharmacother, 125(undefined), 109977. doi:10.1016/j.biopha.2020.109977
Meng Xin., Dong Honghong., Pan Yiwu., Ma Long., Liu Changxiao., Man Shuli., Gao Wenyuan.(2019). Diosgenyl Saponin Inducing Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptotic Pathways in Liver Cancer Cells. J Agric Food Chem, 67(41), 11428-11435. doi:10.1021/acs.jafc.9b05131
Cui Jingxia., Man Shuli., Cui Nina., Yang Li., Guo Qianbei., Ma Long., Gao Wenyuan.(2019). The synergistic anticancer effect of formosanin C and polyphyllin VII based on caspase-mediated cleavage of Beclin1 inhibiting autophagy and promoting apoptosis. Cell Prolif, 52(1), e12520. doi:10.1111/cpr.12520
Man Shuli., Zhang Lili., Cui Jingxia., Yang Li., Ma Long., Gao Wenyuan.(2018). Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells. Cell Prolif, 51(4), e12458. doi:10.1111/cpr.12458
Qu Zhuo., Zhang Jingze., Yang Honggai., Gao Jing., Chen Hong., Liu Changxiao., Gao Wenyuan.(2017). Prunella vulgaris L., an Edible and Medicinal Plant, Attenuates Scopolamine-Induced Memory Impairment in Rats. J Agric Food Chem, 65(2), 291-300. doi:10.1021/acs.jafc.6b04597
ResearcherID Publications
Year Title Author(s) Source Volume
2014 Chemical Constituents of Plants from the Genus Paris Wei, Jin-Chao; Gao, Wen-Yuan; Yan, Xiao-Dan; et al. Chemistry & Biodiversity 11
2014 Changes in main nutrients and medicinal composition of Chinese yam (Dioscorea opposita) tubers during storage Zhang, Zhidan; Gao, Wenyuan; Wang, Renfang; et al. Journal of Food Science and Technology-Mysore 51
2014 Antioxidant Activity Relationships of Pachymaran Derivatives Li, Xia; Gao, Wen-Yuan; Cao, Yu; et al. Journal of Food Biochemistry 38
2014 Antitumor pathway of Rhizoma Paridis Saponins based on the metabolic regulatory network alterations in H22 hepatocarcinoma mice Man, Shuli; Fan, Wei; Liu, Zhen; et al. Steroids 84
2014 Bidirectional effects of methanol extract of Wei-Chang-An pill on gastrointestinal transit and the spasmolytic activity on isolated rat jejunum Qu, Zhuo; Zhang, Jingze; Gao, Wenyuan; et al. Journal of Ethnopharmacology 155
2014 Anti-fibrosis and anti-cirrhosis effects of Rhizoma paridis saponins on diethylnitrosamine induced rats Man, Shuli; Fan, Wei; Gao, Wenyuan; et al. Journal of Ethnopharmacology 151
2014 Anti-diarrhoeal activity of methanol extract of Santalum album L. in mice and gastrointestinal effect on the contraction of isolated jejunum in rats Guo, Huimin; Zhang, Jingze; Gao, Wenyuan; et al. Journal of Ethnopharmacology 154
2014 A natural flavonoid glucoside, icariin, regulates Th17 and alleviates rheumatoid arthritis in a murine model. Chi, Liqun; Gao, Wenyuan; Shu, Xiangrong; et al. Mediators of inflammation 2014
2015 Vasorelaxant effects of Shunaoxin pill are mediated by NO/cGMP pathway, HO/CO pathway and calcium channel blockade in isolated rat thoracic aorta Huo, Liqin; Zhang, Jingze; Qu, Zhuo; et al. Journal of Ethnopharmacology 173
2014 A Natural Flavonoid Glucoside, Icariin, Regulates Th17 and Alleviates Rheumatoid Arthritis in a Murine Model Chi, Liqun; Gao, Wenyuan; Shu, Xiangrong; et al. Mediators of Inflammation