Home / People / / Wenyuan Gao

Wenyuan Gao——Professor

Nationality:
CHINA
Phone:
022-87401895
Email:
pharmgao@tju.edu.cn
Office:
Room A502, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
1994 Ph. D. Peking Union Medical College, China
Professional Experience
1994-1998 Assistant and Associate professor Chinese Academy of Medical Sciences and Peking Union Medical College, China
1998-2000 Postdoctoral fellow Chungbuk National University, Korea
2000-2001 Hong Kong Institute of Biotechnology LTD, Hong Kong
2002-2015 Professor Tianjin University, China
Research Area

The research of the Gao group encompasses three main areas, including 1) Production of active constituents by biotechnology in medicinal plants, b) Development of functional products from Traditional Chinese Medicine and natural products, and c) Development of new drugs from Traditional Chinese Medicine and natural products.

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Honors and Awards
Patents
Highlighted Publications
Man Shuli., Yang Li., Xiang Hao., Lu Guanyu., Wang Yijia., Liu Changxiao., Gao Wenyuan.(2020). Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats. Biomed Pharmacother, 125(undefined), 109977. doi:10.1016/j.biopha.2020.109977
Meng Xin., Dong Honghong., Pan Yiwu., Ma Long., Liu Changxiao., Man Shuli., Gao Wenyuan.(2019). Diosgenyl Saponin Inducing Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptotic Pathways in Liver Cancer Cells. J Agric Food Chem, 67(41), 11428-11435. doi:10.1021/acs.jafc.9b05131
Cui Jingxia., Man Shuli., Cui Nina., Yang Li., Guo Qianbei., Ma Long., Gao Wenyuan.(2019). The synergistic anticancer effect of formosanin C and polyphyllin VII based on caspase-mediated cleavage of Beclin1 inhibiting autophagy and promoting apoptosis. Cell Prolif, 52(1), e12520. doi:10.1111/cpr.12520
Man Shuli., Zhang Lili., Cui Jingxia., Yang Li., Ma Long., Gao Wenyuan.(2018). Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells. Cell Prolif, 51(4), e12458. doi:10.1111/cpr.12458
Qu Zhuo., Zhang Jingze., Yang Honggai., Gao Jing., Chen Hong., Liu Changxiao., Gao Wenyuan.(2017). Prunella vulgaris L., an Edible and Medicinal Plant, Attenuates Scopolamine-Induced Memory Impairment in Rats. J Agric Food Chem, 65(2), 291-300. doi:10.1021/acs.jafc.6b04597
ResearcherID Publications
Year Title Author(s) Source Volume
2014 Synergistic effects of Rhizoma Paridis and Rhizoma Curcuma longa on different animal tumor models Liu, Zhen; Gao, Wenyuan; Man, Shuli; et al. Environmental Toxicology and Pharmacology 38
2014 Pharmacokinetic study on costunolide and dehydrocostuslactone after oral administration of traditional medicine Aucklandia lappa Decne. by LC/MS/MS Zhang, Jingze; Hu, Xiao; Gao, Wenyuan; et al. Journal of Ethnopharmacology 151
2014 Identification of Chemical Constituents in the Extract and Rat Serum from Ziziphus Jujuba Mill. by HPLC-PDA-ESI-MSn Wang, Shuping; Zhang, Jingze; Zhang, Zhidan; et al. Iranian Journal of Pharmaceutical Research 13
2014 Optimization and quality assessment of adventitious roots culture in Panax quinquefolium L. Liu, Hui; Wang, Juan; Gao, Wenyuan; et al. Acta Physiologiae Plantarum 36
2014 Gastrointestinal effect of methanol extract of Radix Aucklandiae and selected active substances on the transit activity of rat isolated intestinal strips Guo, Huimin; Zhang, Jingze; Gao, Wenyuan; et al. Pharmaceutical Biology 52
2014 Evaluation of three traditional Chinese medicine (TCM) starches and potential application in health product industry Li, Xia; Xia, Yuzhuo; Gao, Wenyuan; et al. Food Hydrocolloids 40
2014 Comparative susceptibilities to alkali-treatment of A-, B- and C-type starches of Dioscorea zingiberensis, Dioscorea persimilis and Dioscorea opposita Jiang, Qianqian; Gao, Wenyuan; Li, Xia; et al. Food Hydrocolloids 39
2014 Effects of nitrogen source and phosphate concentration on biomass and metabolites accumulation in adventitious root culture of Glycyrrhiza uralensis Fisch Yin, Shuangshuang; Zhang, Yao; Gao, Wenyuan; et al. Acta Physiologiae Plantarum 36
2014 Combination therapy of cyclophosphamide and Rhizoma Paridis Saponins on anti-hepatocarcinoma mice and effects on cytochrome p450 enzyme expression Man, Shuli; Li, Yuanyuan; Fan, Wei; et al. Steroids 80
2014 Chemical composition and antioxidant and anti-inflammatory potential of peels and flesh from 10 different pear varieties (Pyrus spp.) Li, Xia; Wang, Tingting; Bin Zhou; et al. Food Chemistry 152