Youcai Zhang——Professor |
|
|
Nationality:
|
CHINA
|
|
Phone:
|
022-87401830
|
|
Email:
|
youcai.zhang@tju.edu.cn
|
|
Office:
|
Room 3107, Building 24, Tianjin University
|
|
School:
|
School of Pharmaceutical Science and Technology
|
|
ResearcherID:
|
|
| 2011 | Ph. D. Pharmacology and Toxicology | University of Kansas Medical Center |
| 2013-2014 | Postdoctoral Bioengineering | University of California San Francisco |
| 2011-2013 | Associate Scientist | Elan Pharmaceutics Inc |
| 2013-2014 | Principle Scientist | Apricity Therapeutics |
| Associate Editor, Toxicological Sciences |
| Editor board member, Journal of Lipid Research |
| Xu T, Li X, Zhao W, Wang X, Jin L, Feng Z, Li H, Zhang M, Tian Y, Hu G, Yue Y, Dai X, Shan C, Zhang W, Zhang C, Zhang Y. SF3B3-regulated mTOR alternative splicing promotes colorectal cancer progression and metastasis, Journal of Experimental&Clinical Cancer Research, 2024 |
| Zhao W, Wang X, Han L, Zhang C, Wang C, Kong D, Zhang M, Xu T, Li G, Hu G, Luo J, Yee SW, Yang J, Stahl A, Chen X, Zhang Y. SLC13A3 is a major effector downstream of activated β-catenin in liver cancer pathogenesis, Nature Communications, 2024 |
| Hui Xiong, Chunze Zhang, Lifeng Han, Tong Xu, Khawar Saeed, Jing Han, Jing Liu, Curtis D. Klaassen, Frank J Gonzalez, Yuanfu Lu, Youcai Zhang, Suppressed farnesoid X receptor by iron overload in mice and humans potentiates iron-induced hepatotoxicity, Hepatology, 2022 |
| Year | Title | Author(s) | Source | Volume |
|---|---|---|---|---|
| 2015 | Importance of Large Intestine in Regulating Bile Acids and Glucagon-Like Peptide-1 in Germ-Free Mice. | Selwyn, Felcy Pavithra; Csanaky, Ivan L; Zhang, Youcai; et al. | Drug metabolism and disposition: the biological fate of chemicals | 43 |
| 2015 | Prediction and validation of enzyme and transporter off-targets for metformin | Yee, Sook Wah; Lin, Lawrence; Merski, Matthew; et al. | Journal of Pharmacokinetics and Pharmacodynamics | 42 |
| 2014 | Decreased Bile-Acid Synthesis in Livers of Hepatocyte-Conditional NADPH-Cytochrome P450 Reductase-Null Mice Results in Increased Bile Acids in Serum | Cheng, Xingguo; Zhang, Youcai; Klaassen, Curtis D. | Journal of Pharmacology and Experimental Therapeutics | 351 |
| 2014 | Effect of various antibiotics on modulation of intestinal microbiota and bile acid profile in mice | Zhang, Youcai; Limaye, Pallavi B.; Renaud, Helen J.; et al. | Toxicology and Applied Pharmacology | 277 |
| 2014 | OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin | Chen, Ligong; Shu, Yan; Liang, Xiaomin; et al. | Proceedings of the National Academy of Sciences of the United States of America | 111 |
| 2013 | Hormonal regulation of Cyp4a isoforms in mouse liver and kidney | Zhang, Youcai; Klaassen, Curtis D. | Xenobiotica | 43 |
| 2013 | Oleanolic acid alters bile acid metabolism and produces cholestatic liver injury in mice | Liu, Jie; Lu, Yuan-Fu; Zhang, Youcai; et al. | Toxicology and Applied Pharmacology | 272 |
| 2013 | Organic anion-transporting polypeptide 1a4 (Oatp1a4) is important for secondary bile acid metabolism | Zhang, Youcai; Csanaky, Ivan L.; Selwyn, Felcy Pavithra; et al. | Biochemical Pharmacology | 86 |
| 2013 | Reduced Renal Clearance of Cefotaxime in Asians with a Low-Frequency Polymorphism of OAT3 (SLC22A8) | Yee, Sook Wah; Anh Nguyet Nguyen; Brown, Chaline; et al. | Journal of Pharmaceutical Sciences | 102 |
| 2012 | Dysfunction of Organic Anion Transporting Polypeptide 1a1 Alters Intestinal Bacteria and Bile Acid Metabolism in Mice | Zhang, Youcai; Limaye, Pallavi B.; Lehman-McKeeman, Lois D.; et al. | Plos One | 7 |
