TJU HEALTH SCIENCES PLATFORM

Introduction

Shende Jiang ——Professor
Nationality:	P. R. CHINA
Phone:	022-27892860
Email:	sjiang@tju.edu.cn
Office:	Previously Room A509, Building 24, Weijin Road Campus, Tianjin University
School:	School of Pharmaceutical Science and Technology
ResearcherID:	K-1671-2015
Group weblink
	http://jiang.tju.edu.cn

Education Experience

1979-1983	B.Sc. Chemistry	Liaocheng Normal College
1983-1986	Master of Science Medicinal Chemistry	Shandong Medical University
1992-1996	Doctor of Philosophy Organic Chemistry	University of Teesside

Professional Experience

1986-1988	Lecturer	Shandong Normal University
1988-1990	Leverhulme Trust Research Fellow	Department of Continuing Education, University of Nottingham
1990-1991	Leverhulme Trust Research Fellow	Department of Chemistry, University of Nottingham
1991-1992	Research Fellow	Department of Chemistry, Nottingham Polytechnic
1996-2002	Postdoc Researcher	School of Pharmacy, University of Sunderland
2002-2003	Research Associate	Heriot-Watt University
2003-2004	Research Associate	University of Newcastle upon Tyne
2004-	Professor of Medicinal Chemistry	Tianjin University

Research Area

The research of the Jiang group includes, a) carbohydrate chemistry with the use of sugars as chiral starting materials in synthesis, b) studies on the shikimic acid and shikimate pathway with particular interests in designing enzyme inhibitors as potential antimicrobial agents against bacterial, fungal and parasitical pathogens, c) process research and development for Active Pharmaceutical Ingredients and related intermediates in collaboration with industry, and d) development of fluorine-18 labelled radiopharmaceuticals used in Positron Emission Tomography

Honors and Awards

Patents

Highlighted Publications

Yao, S.; Hu, K.; Tang, G.; Liang, X.; Du, K.; Nie, D.; Jiang, S.; Zang, L. Positron emission tomography imaging of cell death with [18F]FPDuramycin. Apoptosis 2014, 19, 841.

Liu, C.; Kang, H.; Wightman, R. H.; Jiang, S. Stereoselective synthesis of a novel Galf-disaccharide mimic:β-D-galactofuranosyl-(1-5)-β-D-galactofuranosyl motif of mycobacterial cell walls. Tetrahedron Lett. 2013, 54, 1192.

Wang, H.; Guo, X.; Jiang, S.; Tang, G. Automated synthesis of [18F] Florbetaben as Alzheimer’s disease imaging agent based on a synthesis module system. Appl. Radiat. Isotopes 2013, 71, 41.

Geng, H.; Chen, J. L-Y.; Furkert, D. P.; Jiang, S.; Brimble, M. A. A Covergent Synthesis of the 2-Formylpyrrole Spiroketal Natural Product Acortatarin A. Synlett 2012, 23, 855.

Wang, H.; Shi, H.; Yu, H.; Jiang S.; Tang, G. Facile and rapid one-step radiosynthesis of [18F]BAY94-9172 with a new precursor. Nucl. Med. Biol. 2011, 38, 121.

ResearcherID Publications

Year	Title	Author(s)	Source	Volume
2015	Lewis Acid Catalyzed Intramolecular [3 2] Cross Cycloadditions of Cobalt-Alkynylcyclopropane 1,1-Diesters with Carbonyls for Construction of Medium-Sized and Polycyclic Skeletons	Zhang, Junhui; Xing, Siyang; Ren, Jun; et al.	Organic Letters	17
2015	Molecular PET Imaging of Cyclophosphamide Induced Apoptosis with 18F-ML-8.	Yao, Shaobo; Hu, Kongzhen; Tang, Ganghua; et al.	BioMed research international	2015
2015	Molecular PET Imaging of Cyclophosphamide Induced Apoptosis with F-18-ML-8	Yao, Shaobo; Hu, Kongzhen; Tang, Ganghua; et al.	Biomed Research International
2014	Positron emission tomography imaging of cell death with [F-18]FPDuramycin	Yao, Shaobo; Hu, Kongzhen; Tang, Ganghua; et al.	Apoptosis	19
2014	Synthesis and Antimetastatic Effects of E-Salignone Amide Derivatives	Wang, Hong-Ling; Qin, Nan; Liu, Jia; et al.	Drug Development Research	75
2005	Plasmodium falciparum: Interaction of shikimate analogues with antimalarial drugs	McRobert, L; Jiang, SD; Stead, A; et al.	Experimental Parasitology	111
2005	Synthesis of (6S)-fluoroshikimic acid (Retraction of vol 14, pg 2833, 2003)	Song, CJ; Jiang, SD; Singh, G	Tetrahedron-Asymmetry	16
2004	Syntheses of ethyl 3-deoxy-3,3-difluoro-D-arabino-heptulosonate and analogues	Li, Y; Drew, MGB; Welchman, EV; et al.	Tetrahedron	60
2003	Synthesis of (6S)-6-fluoroshikimic acid (Retracted Article. See vol 16, pg. 2832, 2005)	Song, C; Jiang, S; Singh, G	Tetrahedron-Asymmetry	14
2002	Facile syntheses of (6S)-6-fluoroshikimic acid and (6R)-6-hydroxyshikimic acid	Song, CJ; Jiang, SD; Singh, GD	Chemical Research in Chinese Universities	18
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Shende Jiang ——Professor

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