TJU HEALTH SCIENCES PLATFORM

Introduction

Shende Jiang ——Professor
Nationality:	P. R. CHINA
Phone:	022-27892860
Email:	sjiang@tju.edu.cn
Office:	Previously Room A509, Building 24, Weijin Road Campus, Tianjin University
School:	School of Pharmaceutical Science and Technology
ResearcherID:	K-1671-2015
Group weblink
	http://jiang.tju.edu.cn

Education Experience

1979-1983	B.Sc. Chemistry	Liaocheng Normal College
1983-1986	Master of Science Medicinal Chemistry	Shandong Medical University
1992-1996	Doctor of Philosophy Organic Chemistry	University of Teesside

Professional Experience

1986-1988	Lecturer	Shandong Normal University
1988-1990	Leverhulme Trust Research Fellow	Department of Continuing Education, University of Nottingham
1990-1991	Leverhulme Trust Research Fellow	Department of Chemistry, University of Nottingham
1991-1992	Research Fellow	Department of Chemistry, Nottingham Polytechnic
1996-2002	Postdoc Researcher	School of Pharmacy, University of Sunderland
2002-2003	Research Associate	Heriot-Watt University
2003-2004	Research Associate	University of Newcastle upon Tyne
2004-	Professor of Medicinal Chemistry	Tianjin University

Research Area

The research of the Jiang group includes, a) carbohydrate chemistry with the use of sugars as chiral starting materials in synthesis, b) studies on the shikimic acid and shikimate pathway with particular interests in designing enzyme inhibitors as potential antimicrobial agents against bacterial, fungal and parasitical pathogens, c) process research and development for Active Pharmaceutical Ingredients and related intermediates in collaboration with industry, and d) development of fluorine-18 labelled radiopharmaceuticals used in Positron Emission Tomography

Honors and Awards

Patents

Highlighted Publications

Yao, S.; Hu, K.; Tang, G.; Liang, X.; Du, K.; Nie, D.; Jiang, S.; Zang, L. Positron emission tomography imaging of cell death with [18F]FPDuramycin. Apoptosis 2014, 19, 841.

Liu, C.; Kang, H.; Wightman, R. H.; Jiang, S. Stereoselective synthesis of a novel Galf-disaccharide mimic:β-D-galactofuranosyl-(1-5)-β-D-galactofuranosyl motif of mycobacterial cell walls. Tetrahedron Lett. 2013, 54, 1192.

Wang, H.; Guo, X.; Jiang, S.; Tang, G. Automated synthesis of [18F] Florbetaben as Alzheimer’s disease imaging agent based on a synthesis module system. Appl. Radiat. Isotopes 2013, 71, 41.

Geng, H.; Chen, J. L-Y.; Furkert, D. P.; Jiang, S.; Brimble, M. A. A Covergent Synthesis of the 2-Formylpyrrole Spiroketal Natural Product Acortatarin A. Synlett 2012, 23, 855.

Wang, H.; Shi, H.; Yu, H.; Jiang S.; Tang, G. Facile and rapid one-step radiosynthesis of [18F]BAY94-9172 with a new precursor. Nucl. Med. Biol. 2011, 38, 121.

ResearcherID Publications

Year	Title	Author(s)	Source	Volume
2002	Glycosylation based on glycosyl phosphates as glycosyl donors	Vankayalapati, H; Jiang, SD; Singh, G	Synlett
2001	Syntheses of (-)-MK7607 and other carbasugars from (-)-shikimic acid	Song, CJ; Jiang, SD; Singh, G	Synlett
2001	Syntheses of (6S)-6-fluoro- and (6R)-6-hydroxyshikimic acids	Song, CJ; Jiang, SD; Singh, G	Tetrahedron Letters	42
2000	General and efficient syntheses of C-18-4,8-sphingadienines via S(N)2 ’-type homoallylic coupling reactions mediated by thioether-stabilized copper reagents	Wang, XZ; Wu, YL; Jiang, SD; et al.	Journal of Organic Chemistry	65
2000	Synthesis of a difluorinated carbasugar from D-ribose via intramolecular nitrone cycloaddition reaction	Jiang, S; Singh, G; Batsanov, AS	Tetrahedron-Asymmetry	11
1999	Synthesis of (2S,3R,4E,8E)-9-methyl-4,8-sphingadienine via a novel S(N)2 ’ type reaction mediated by a thioether carbanion	Wang, XZ; Wu, YL; Jiang, SD; et al.	Tetrahedron Letters	40
1999	Synthesis of 3-deoxy-3,3-difluoroshikimic acid and its 4-epimer from quinic acid	Jiang, S; Singh, G; Boam, DJ; et al.	Tetrahedron-Asymmetry	10
1998	Chemical synthesis of shikimic acid and its analogues	Jiang, SD; Singh, G	Tetrahedron	54
1998	General syntheses of ethyl 2-ulosonates and 3-deoxy-D-manno-oct-2-ulosonic acid from carbohydrate lactones with 1-ethoxyvinyllithium	Jiang, SD; Rycroft, AD; Singh, G; et al.	Tetrahedron Letters	39
1997	Enantiospecific synthesis of (-)-5-epi-shikimic acid and (-)-shikimic acid	Jiang, SD; McCullough, KJ; Mekki, B; et al.	Journal of the Chemical Society-Perkin Transactions 1
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Shende Jiang ——Professor

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