Fumihiko Nakamura——Professor |
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Nationality:
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Phone:
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Email:
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fnakamura@tju.edu.cn
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Office:
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B210, 2F Building 24, School of Pharmaceutical Science and Technology, Tianjin University
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School:
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School of Pharmaceutical Science and Technology
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ResearcherID:
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1990-1993 | Ph. D. Animal Science | Tohoku University, Japan |
1994-1995 | Postdoctoral Cell Biology | Stanford University |
1995-2000 | Associate Professor | Tohoku University |
2001-2005 | Research Fellow | Brigham and Women's Hospital/Harvard Medical School |
2006-2008 | Instructor | Brigham and Women's Hospital/Harvard Medical School |
2008-2016 | Assistant Professor | Brigham and Women's Hospital/Harvard Medical School |
2016- | Professor | Tianjin University |
Japan society for the promotion of science for Japanese junior scientists |
Nissan Science Foundation, Japan |
Kurita Water and Environment Foundation, Japan |
Naito Foundation, Japan |
The HUSEC grant for an interdisciplinary seed proposal project, Harvard University, USA |
Mao, Z., and *Nakamura, F. Structure and Function of Filamin C in the Muscle Z-Disc, Int J Mol Sci, 2020; 21 |
Wang, J., *Nakamura, F. Identification of Filamin A Mechanobinding Partner II: Fimbacin Is a Novel Actin Cross-Linking and Filamin A Binding Protein, Biochemistry, 2019, 10.1021/acs.biochem.9b00101 |
Wang, L., *Nakamura, F. Identification of Filamin A Mechanobinding Partner I: Smoothelin Specifically Interacts with the Filamin A Mechanosensitive Domain 21, Biochemistry, 2019, 10.1021/acs.biochem.9b00100 |
*Nakamura, F. Mechanotransduction in blood cells. Asia-Pacific Journal of Blood Types and Genes, 2017;1(1):1-9 |
*Nakamura F, Song M, Hartwig JH, Stossel TP. Documentation and localization of force-mediated filamin A domain perturbations in moving cells. Nat Commun. 2014;5:4656 PMID 25120197, PMC 4139033 |
*Nakamura F. FilGAP and its close relatives: a mediator of Rho-Rac antagonism that regulates cell morphology and migration. Biochem J. 2013;453(1):17-25 PMID 23763313 |
Ehrlicher AJ, *Nakamura F (co-first and corresponding author), Hartwig JH, Weitz DA, Stossel TP. Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A. Nature. 2011 PMID 21926999 |
Playford MP, Nurminen E, Pentikainen OT, Milgram SL, Hartwig JH, Stossel TP, *Nakamura F. Cystic fibrosis transmembrane conductance regulator interacts with multiple immunoglobulin domains of filamin A. J Biol Chem. 2010;285(22):17156-65 PMID 20351098, PMC 2878090 |
*Nakamura F, Osborn TM, Hartemink CA, Hartwig JH, Stossel TP. Structural basis of filamin A functions. J Cell Biol. 2007;179(5):1011-25 PMID 18056414 |
Nakamura F, Pudas R, Heikkinen O, Permi P, Kilpelainen I, Munday AD, Hartwig JH, Stossel TP, Ylanne J. The structure of the GPIb-filamin A complex. Blood. 2006;107(5):1925-32 PMID 16293600 |
Hishiya A, Ohnishi M, Tamura S, *Nakamura F. Protein phosphatase 2C inactivates F-actin binding of human platelet Moesin. J Biol Chem. 1999;274(38):26705-12 |
Nakamura F, Huang L, Pestonjamasp K, Luna EJ, Furthmayr H. Regulation of F-actin binding to platelet moesin In vitro by both phosphorylation of threonine 558 and polyphosphatidylinositides. Mol Biol Cell. 1999;10(8):2669-85 |
Year | Title | Author(s) | Source | Volume |
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2013 | FilGAP and its close relatives: a mediator of Rho-Rac antagonism that regulates cell morphology and migration | Nakamura, Fumihiko | Biochemical Journal | 453 |
2013 | Mechanical perturbation of filamin A immunoglobulin repeats 20-21 reveals potential non-equilibrium mechanochemical partner binding function | Chen, Hu; Chandrasekar, Saranya; Sheetz, Michael P.; et al. | Scientific Reports | 3 |
2012 | Electron Microscopy and 3D Reconstruction Reveals Filamin Ig Domain Binding to F-Actin | Suphamungmee, Worawit; Nakamura, Fumihiko; Hartwig, John H.; et al. | Journal of Molecular Biology | 424 |
2011 | Differential Mechanical Stability of Filamin A Rod Segments | Chen, Hu; Zhu, Xiaoying; Cong, Peiwen; et al. | Biophysical Journal | 101 |
2011 | Improved High-Force Magnetic Tweezers for Stretching and Refolding of Proteins and Short DNA | Chen, Hu; Fu, Hongxia; Zhu, Xiaoying; et al. | Biophysical Journal | 100 |
2011 | Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A | Ehrlicher, A. J.; Nakamura, F.; Hartwig, J. H.; et al. | Nature | 478 |
2011 | Refilin holds the cap. | Gay, Olivia; Nakamura, Fumihiko; Baudier, Jacques | Communicative & integrative biology | 4 |
2011 | RefilinB (FAM101B) targets FilaminA to organize perinuclear actin networks and regulates nuclear shape | Gay, Olivia; Gilquin, Benoit; Nakamura, Fumihiko; et al. | Proceedings of the National Academy of Sciences of the United States of America | 108 |
2011 | The filamins Organizers of cell structure and function | Nakamura, Fumihiko; Stossel, Thomas P.; Hartwig, John H. | Cell Adhesion & Migration | 5 |
2010 | Actin Filament Length Tunes Elasticity of Flexibly Cross-Linked Actin Networks | Kasza, K. E.; Broedersz, C. P.; Koenderink, G. H.; et al. | Biophysical Journal | 99 |