TJU HEALTH SCIENCES PLATFORM

Introduction

Jianhui Huang——Professor
Nationality:	CHINA
Phone:	022-27409894
Email:	jhuang@tju.edu.cn
Office:	Office 514C, Building 24, Tianjin University
School:	School of Pharmaceutical Science and Technology
ResearcherID:	H-1552-2011
Group weblink
	http://huang.tju.edu.cn

Education Experience

2003-2006	Doctor of Philosophy Chemistry	University of York, UK
1996-2000	Bachelor of Science Chemistry	Hu'nan University

Professional Experience

2007-2010	Postdoctorial Research Associate	University of Sheffield and GlaxoSmithKlein
2010-2023	Associate Professor/Professor	Tianjin University, China

Research Area

The research of the Huang group encompasses the following main areas:

1) Molecular design (AIDD & Chiral Catalyst/ligand Design)

2) XDC Drug Development and Preparation (Protac/RDC...)

3) New Chemical Space Exploration

Honors and Awards

Teaching Award, HSP, Tianjin University, 2018

Thieme Chemistry Journal Award, 2017

Best Publication Award, HSP, Tianjin University, 2015

Patents

黄剑辉; 刘柳; 曾凡云; 陈晨; 李一凡 ; 手性二胺类化合物和应用以及亚胺的不对称加成方法, 2021-04-14, 中国, ZL202110401309.1 (专利)

钌催化下的2－（3－溴苯基）吡啶类衍生物的合成， 2015031900635430，黄剑辉、于庆贞、胡乐安、王悦、赵康， 2016.09

3-羟基-2-烷氧基-3-苯基异吲哚-1(2H)-酮类衍生物的制备方法， 2013102117068，黄剑辉、刘伟东、朱怡、于庆贞、张娜娜， 2015.07

Highlighted Publications

Qing Wang,† Fanhao Meng,† Yuting Xie, Wei Wang, Yumin Meng, Linjie Li, Tao Liu, Jianxun Qi, Xiaodan Ni, Sanduo Zheng, Jianhui Huang,* Niu Huang.* In Silico Discovery of Small Molecule Modulators Targeting the Achilles' Heel of SARS-CoV- 2 Spike Protein. ACS Cent. Sci. 2023. 9, 252–265. doi: 10.1021/acscentsci.2c01190.

Xiaoli Qin, Lin Huang, Ziying Zhan, Peng Fu, Congyang Zhang, Jianhui Huang, Zhifeng Ding.“Enhancing corannulene electrochemiluminescence and chemiluminescence by means of an Azabora-helicene to slow down its bowl inversion.” Chem. Sci., 2024, accepted.

Lin Huang, Qing Wang, Peng Fu, Yuzhu Sun, Duncan Browne, Jianhui Huang. “Extended Quinolizinium-Fused Corannulene Derivatives: Synthesis and Properties.”JACS Au (An Open Access Journal of The American Chemical Society), 2024, 4, 1623-1631.

Lin Huang. Mengyu Qiu, Zhihao Chang, Duncan Browne, Jianhui Huang.“C–H Activation Enabled Piperazine-Embedded Azadibenzo[a,g]corannulene Synthesis.”Org. Chem. Front., 2024, 11, 2807-2814.

Q. Yu; L. Hu; Y. Wang; S. Zheng; J. Huang "Directed meta-selective bromination of arenes with ruthenium catalysts." Angew. Chem. Int. Ed., 2015, 54, 15284-15288.

ResearcherID Publications

Year	Title	Author(s)	Source	Volume
2018	Preparation of Thioanisole Biscarbanion and C-H Lithiation/Annulation Reactions for the Access of Five-Membered Heterocycles	Zhu, Ranran; Liu, Zheyuan; Chen, Jie; et al.	Organic Letters	20
2018	Norbornene in Organic Synthesis	Li, Caifeng; Liu, Liu; Fu, Xuegang; et al.	Synthesis-Stuttgart	50
2018	Direct Double Arylation of Bridged Alkenes and Efficient Bis-C-H Alkylation of Benzamides	Zhao, Xiaoxia; Bai, Jinshan; Zeng, Fanyun; et al.	Chemistryselect	3
2008	A [4 2] cycloaddition strategy to pyridine boronic ester derivatives	Delaney, Patrick M.; Huang, Jianhui; Macdonald, Simon J. F.; et al.	Organic Letters	10
2006	Two-step synthesis of N-sulfonyl aziridines from epoxides	Huang, JH; O’Brien, P	Synthesis-Stuttgart
2005	Organolithium-mediated conversion of beta-functionalised aziridines into alkynyl amino alcohols and diamines	Huang, JH; O’Brien, P	Chemical Communications
2005	Two-step syntheses of 2,4,6-triisopropylbenzenesulfonyl aziridines	Huang, JH; O’Brien, P	Tetrahedron Letters	46
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Jianhui Huang——Professor

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