Home / People / / Wenyuan Gao

Wenyuan Gao——Professor

Nationality:
CHINA
Phone:
022-87401895
Email:
pharmgao@tju.edu.cn
Office:
Room A502, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
1994 Ph. D. Peking Union Medical College, China
Professional Experience
1994-1998 Assistant and Associate professor Chinese Academy of Medical Sciences and Peking Union Medical College, China
1998-2000 Postdoctoral fellow Chungbuk National University, Korea
2000-2001 Hong Kong Institute of Biotechnology LTD, Hong Kong
2002-2015 Professor Tianjin University, China
Research Area

The research of the Gao group encompasses three main areas, including 1) Production of active constituents by biotechnology in medicinal plants, b) Development of functional products from Traditional Chinese Medicine and natural products, and c) Development of new drugs from Traditional Chinese Medicine and natural products.

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Honors and Awards
Patents
Highlighted Publications
Man Shuli., Yang Li., Xiang Hao., Lu Guanyu., Wang Yijia., Liu Changxiao., Gao Wenyuan.(2020). Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats. Biomed Pharmacother, 125(undefined), 109977. doi:10.1016/j.biopha.2020.109977
Meng Xin., Dong Honghong., Pan Yiwu., Ma Long., Liu Changxiao., Man Shuli., Gao Wenyuan.(2019). Diosgenyl Saponin Inducing Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptotic Pathways in Liver Cancer Cells. J Agric Food Chem, 67(41), 11428-11435. doi:10.1021/acs.jafc.9b05131
Cui Jingxia., Man Shuli., Cui Nina., Yang Li., Guo Qianbei., Ma Long., Gao Wenyuan.(2019). The synergistic anticancer effect of formosanin C and polyphyllin VII based on caspase-mediated cleavage of Beclin1 inhibiting autophagy and promoting apoptosis. Cell Prolif, 52(1), e12520. doi:10.1111/cpr.12520
Man Shuli., Zhang Lili., Cui Jingxia., Yang Li., Ma Long., Gao Wenyuan.(2018). Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells. Cell Prolif, 51(4), e12458. doi:10.1111/cpr.12458
Qu Zhuo., Zhang Jingze., Yang Honggai., Gao Jing., Chen Hong., Liu Changxiao., Gao Wenyuan.(2017). Prunella vulgaris L., an Edible and Medicinal Plant, Attenuates Scopolamine-Induced Memory Impairment in Rats. J Agric Food Chem, 65(2), 291-300. doi:10.1021/acs.jafc.6b04597
ResearcherID Publications
Year Title Author(s) Source Volume
2012 Steroidal saponins from the rhizomes of Trillium tschonoskii Maxim. Wei, Jin-Chao; Man, Shu-Li; Gao, Wen-Yuan; et al. Biochemical Systematics and Ecology 44
2012 Simultaneous quantification of Polyphyllin D and Paris H, two potential antitumor active components in Paris polyphylla by liquid chromatography-tandem mass spectrometry and the application to pharmacokinetics in rats Wu, Shanshan; Gao, Wenyuan; Qiu, Feng; et al. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 905
2012 Quantification of four active ingredients and fingerprint analysis of Licorice (Glycyrrhiza uralensis Fisch.) after spaceflight by HPLC-DAD Dong, Yan-Yan; Gao, Wen-Yuan; Zhang, Jing-Ze; et al. Research on Chemical Intermediates 38
2012 Production of ginsenoside and polysaccharide by two-stage cultivation of Panax quinquefolium L. cells Wang, Juan; Gao, Wen-Yuan; Zhang, Jian; et al. In Vitro Cellular & Developmental Biology-Plant 48
2012 Pharmacological evaluation of sedative-hypnotic activity and gastro-intestinal toxicity of Rhizoma Paridis saponins Liu, Zhen; Gao, Wenyuan; Man, Shuli; et al. Journal of Ethnopharmacology 144
2012 Physicochemical, crystalline, and thermal properties of native and enzyme hydrolyzed Pueraria lobata (Willd.) Ohwi and Pueraria thomsonii Benth. starches Xia, Yuzhuo; Gao, Wenyuan; Jiang, Qianqian; et al. Starch-Starke 64
2012 Physicochemical, morphological, structural, and thermal characteristics of starches separated from Bulbus fritillaria of different cultivars Li, Xia; Gao, Wenyuan; Jiang, Qianqian; et al. Starch-Starke 64
2012 Effects of Space Flight on the Chemical Constituents and Anti-Inflammatory Activity of Licorice (Glycyrrhiza uralensis Fisch) Zhang, Jingze; Gao, Wenyuan; Yan, Shuo; et al. Iranian Journal of Pharmaceutical Research 11
2012 Effects of sucrose concentration and exogenous hormones on growth and periplocin accumulation in adventitious roots of Periploca sepium Bunge Zhang, Jian; Gao, Wen-Yuan; Wang, Juan; et al. Acta Physiologiae Plantarum 34
2012 Gradually scale-up culture in a bioreactor promotes radical scavenging activity of Panax ginseng (C. A. Meyer) adventitious roots on 1,1-diphenyl-2-picrylhydrazyl Wang, Juan; Gao, Wenyuan; Zuo, Beimei; et al. Plant Growth Regulation 67