Home / People / / Wenyuan Gao

Wenyuan Gao——Professor

Nationality:
CHINA
Phone:
022-87401895
Email:
pharmgao@tju.edu.cn
Office:
Room A502, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
1994 Ph. D. Peking Union Medical College, China
Professional Experience
1994-1998 Assistant and Associate professor Chinese Academy of Medical Sciences and Peking Union Medical College, China
1998-2000 Postdoctoral fellow Chungbuk National University, Korea
2000-2001 Hong Kong Institute of Biotechnology LTD, Hong Kong
2002-2015 Professor Tianjin University, China
Research Area

The research of the Gao group encompasses three main areas, including 1) Production of active constituents by biotechnology in medicinal plants, b) Development of functional products from Traditional Chinese Medicine and natural products, and c) Development of new drugs from Traditional Chinese Medicine and natural products.

63fb6707d4f18be719da3b85d90bcee.png

Honors and Awards
Patents
Highlighted Publications
Man Shuli., Yang Li., Xiang Hao., Lu Guanyu., Wang Yijia., Liu Changxiao., Gao Wenyuan.(2020). Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats. Biomed Pharmacother, 125(undefined), 109977. doi:10.1016/j.biopha.2020.109977
Meng Xin., Dong Honghong., Pan Yiwu., Ma Long., Liu Changxiao., Man Shuli., Gao Wenyuan.(2019). Diosgenyl Saponin Inducing Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptotic Pathways in Liver Cancer Cells. J Agric Food Chem, 67(41), 11428-11435. doi:10.1021/acs.jafc.9b05131
Cui Jingxia., Man Shuli., Cui Nina., Yang Li., Guo Qianbei., Ma Long., Gao Wenyuan.(2019). The synergistic anticancer effect of formosanin C and polyphyllin VII based on caspase-mediated cleavage of Beclin1 inhibiting autophagy and promoting apoptosis. Cell Prolif, 52(1), e12520. doi:10.1111/cpr.12520
Man Shuli., Zhang Lili., Cui Jingxia., Yang Li., Ma Long., Gao Wenyuan.(2018). Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells. Cell Prolif, 51(4), e12458. doi:10.1111/cpr.12458
Qu Zhuo., Zhang Jingze., Yang Honggai., Gao Jing., Chen Hong., Liu Changxiao., Gao Wenyuan.(2017). Prunella vulgaris L., an Edible and Medicinal Plant, Attenuates Scopolamine-Induced Memory Impairment in Rats. J Agric Food Chem, 65(2), 291-300. doi:10.1021/acs.jafc.6b04597
ResearcherID Publications
Year Title Author(s) Source Volume
2011 Physicochemical Properties of Starches from Two Different Yam (Dioscorea Opposita Thunb.) Residues Wang, Yugao; Zhang, Liming; Li, Xinglin; et al. Brazilian Archives of Biology and Technology 54
2011 Isolation and Identification of Compounds Present in Rhizomes of Paris axialis H. Li and Study of Their Cytotoxic Effects Huang, Xianxiao; Gao, Wenyuan; Man, Shuli; et al. Latin American Journal of Pharmacy 30
2011 Paridis Saponins Inhibiting Carcinoma Growth and Metastasis In Vitro and In Vivo Man, Shuli; Gao, Wenyuan; Zhang, Yanjun; et al. Archives of Pharmacal Research 34
2011 Inhibition of matrix metalloproteinases related to metastasis by diosgenyl and pennogenyl saponins Man, Shuli; Gao, Wenyuan; Yan, Yanjun; et al. Journal of Ethnopharmacology 137
2011 In vivo Anti-inflammatory and In vitro Antioxidant Potential of Crude Fractions from Pyrus bretschneideri Rehd. Li, Xia; Gao, Wenyuan; Huang, Lijing Latin American Journal of Pharmacy 30
2011 Influence of Crown tiglium Seeds on the Pharmacokinetics of Anthraquinones in Radix et Rhizoma Rhei Zhang, Jingze; Gao, Wenyuan; Ma, Chaoyi; et al. Latin American Journal of Pharmacy 30
2011 Identification of chemical constituents in Rhizoma Paridis Saponins and their oral administration in rat plasma by UPLC/Q-TOF/MS Man, Shuli; Gao, Wenyuan; Zhang, Yanjun; et al. Biomedical Chromatography 25
2011 Identification of Urinary and Feces Metabolites of Rhizoma Paridis Saponins in rats based on Ultra High Performance Liquid Chromatography/Time-Of-Flight Mass Spectrometry (UPLC/Q-TOF/MS) Wu, Shanshan; Gao, Wenyuan; Man, Shuli; et al. Latin American Journal of Pharmacy 30
2011 Glycyrrhizic Acid-Phospholipid Complex: Preparation Process Optimization and Therapeutic and Pharmacokinetic Evaluation in Rats Zhang, Jingze; Gao, Wenyuan; Bai, Shufang; et al. Latin American Journal of Pharmacy 30
2011 Identification of Chemical Constituents in Extracts and Rat Plasma from Fructus Aurantii by UPLC-PDA-Q-TOF/MS Ma, Chaoyi; Gao, Wenyuan; Gao, Ying; et al. Phytochemical Analysis 22