Education Experience
2001-2005 |
Bachelor of Science Pharmaceutical |
Tianjin University |
2005-2013 |
Ph. D. Biochemistry and Molecular Biology |
Institute of Biophysics, CAS |
Professional Experience
2013-2014 |
Research Assistant |
Institute of Biophysics, CAS
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2014-2015 |
Post-doc |
Institute of Microbiology, CAS
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2015-2019 |
Post-doc |
Boston Children's Hospital / Harvard Medical School
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Research Area
Our laboratory is interested in the cellular innate immune events that sense viral infection and inhibit viral replication. We are particularly focusing on the following two aspects: (1) endogenous suppressors that modulate innate immune signaling, and (2) molecular mechanism of autoimmune disorders caused by aberrant immune responses.
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Highlighted Publications
Mu X, Hur S. Immunogenicity of In Vitro-Transcribed RNA. Acc Chem Res. 2021 Nov 2;54(21):4012-4023. |
Mu X, Greenwald E, Ahmad S, Hur S. An origin of the immunogenicity of in vitro transcribed RNA. Nucleic Acids Res 2018, 46(10):5239-5249. |
Ahmad S*, Mu X*, Yang F*, Greenwald E, Park J W, Jacob E, Zhang C, Hur S. Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation. Cell 2018, 172(4):797-810 e13. (*: co-first author) |
Mu X, Ahmad S, Hur S. Endogenous Retroelements and the Host Innate Immune Sensors. Adv Immunol 2016, 132, 47-69 |
Mu X, Fu Y, Zhu Y, Wang X, Xuan Y, Shang H, Goff SP, Gao G: HIV-1 Exploits the Host Factor RuvB-like 2 to Balance Viral Protein Expression. Cell Host Microbe 2015, 18(2):233-242. |
Mu X*, Li W*, Wang X, Gao G: YB-1 stabilizes HIV-1 genomic RNA and enhances viral production. Protein Cell 2013, 4(8):591-597. (*: co-first author) |
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