My research is focused on two specific areas, one is hydrophobin and another one is biology and disease of urothelium. For the hydrophobin study, my research is involved but not limited to: 1) Study protein-protein interaction and protein assembly in vitro and in vivo. 2) Protein expression, purification and characterization in both prokaryotic and eukaryotic systems.  3) Hydrophobin based drug and gene delivery systems. 4) Hydrophobin based chip and sensors. 5) Antibody production and purification. 6) Large-scale high-density fermentation and downstream separation. For the urothelium study, my research is involved but not limited to: 1) Study the urothelial disease like bacterial urinary tract infection and bladder. 2) study of ATP release channel of urothelium in mouse model. 3) Drug release and delivery by adenovirus and liposome in urothelium. 4) Characterization and function study of lipid raft proteins. 5) Study the stem cell of the urothelium.