Microbiology & Immunology platform focus on the microbiology & immunobiology issues to support the theoretical and methodological research on key pathogenic microorganisms and their pathogenesis and immune mechanisms, and to develop the bio-products (diagnosis reagents, vaccine, adjuvants, therapeutic drug and others) to control infectious diseases. The integrated M & I analysis platform will be constructed to support the life science research and to service the human health in the future.
Research fields:
1.Infection immunity: Structural and functions of viral genomes；Pathogenesis, innate immunity and immune evasion mechanisms of viral infections.
2.Microbial biology in human, animal, food, water and stress environments by epigenetics, comparative genomics and bioinformatics.
3.Regulation and adaptive evolution of key innate immune system during in different biological evolution. Enzymology of immune cells in viral infection and inflammation.
4.Sensing of MAMPs from bacteria, fungi, and viruses or DAMPs by immune PRRs and their compartments. Immune regulation roles of natural adjuvants (microbiota, natural components of commensal lactic acid bacteria, plants) or synthetic agonists on innate immunity.
5.Enzymology of immune cells in viral infection and inflammation. General scheme for the enrichment of microbial cells or biomarkers with affinity probes showed as following figure.
Microbiology & Immunology platform focus on the microbiology & immunobiology issues to support the theoretical and methodological research on key pathogenic microorganisms and their pathogenesis and immune mechanisms, and to develop the bio-products (diagnosis reagents, vaccine, adjuvants, therapeutic drug and others) to control infectious diseases. The integrated M & I analysis platform will be constructed to support the life science research and to service the human health in the future.
Research fields:
1.Infection immunity: Structural and functions of viral genomes；Pathogenesis, innate immunity and immune evasion mechanisms of viral infections.
2.Microbial biology in human, animal, food, water and stress environments by epigenetics, comparative genomics and bioinformatics.
3.Regulation and adaptive evolution of key innate immune system during in different biological evolution. Enzymology of immune cells in viral infection and inflammation.
4.Sensing of MAMPs from bacteria, fungi, and viruses or DAMPs by immune PRRs and their compartments. Immune regulation roles of natural adjuvants (microbiota, natural components of commensal lactic acid bacteria, plants) or synthetic agonists on innate immunity.
5.Enzymology of immune cells in viral infection and inflammation. General scheme for the enrichment of microbial cells or biomarkers with affinity probes showed as following figure.
