TJU HEALTH SCIENCES PLATFORM

Introduction

Jing Wei——Lecturer
Nationality:	CHINA
Phone:	022-87401830
Email:	betty_wj@tju.edu.cn
Office:	Room A205, Building 24, Tianjin University
School:	School of Pharmaceutical Science and Technology
ResearcherID:	K-1108-2015
Group weblink

Education Experience

2001-2004	Master of Engineering Pattern Recognition and Intelligence System	Tianjin University, CN
2004-2007	Doctor of Engineering Medicinal Chemistry	Tianjin University CN

Professional Experience

2007-2015	lecturer	Tanjin University , China
1995-2001	Physician	Laboratorian of Center for Disease Control and Prevention, Hexi District, Tianjin

Research Area

Wei’s research addresses mechanisms of drug activity with associated drug design. Computational approaches (e.g., molecular docking, pharmacophore modeling, quantitative structure-activity relationship (QSAR), molecular dynamics) are used to identify and characterize putative ligand binding sites, elucidate binding mechanisms, and guide rational design of potentially new drugs.

Honors and Awards

魏静，四乙酰核糖和二乙酰阿昔洛韦合成的新工艺，天津市人民政府，科技进步奖，二等奖，2009。（赵康、陈维瑜、魏静、杜云飞、王松青、苏艳芳、张秀东、陈炎泉）

魏静，第十三届“挑战杯”天津市大学生课外学术科技作品竞赛优秀指导教师，天津市委员会、天津市科学技术委员会、天津市教育工作委员会等，2015。

Patents

Highlighted Publications

The comparison of BLyS-binding peptides from phage display library and computer-aided design on BLyS–TACI interaction. Int. Immunopharmacol. 2015, 24 (2) 219–223.

Computer-aided de novo ligand design and docking/molecular dynamics study of Vitamin D receptor agonists. J. Mol. Model., 2012, 18（1）: 203–212.

Docking and molecular dynamics study on the inhibitory activity of novel inhibitors on epidermal growth factor receptor (EGFR). Med Chem. 2011, 7(1):24-31.

Adevances in the study of A2B adenosine receptor antagonists. Anta Pharmaceutica Sinica，2008，43 (3): 241-246.

ResearcherID Publications

Year	Title	Author(s)	Source	Volume
2016	Mechanistic Study of Human Glucose Transport Mediated by GLUT1	Fu, Xuegang; Zhang, Gang; Liu, Ran; et al.	Journal of Chemical Information and Modeling	56
2016	A Novel BLyS Peptibody Down-Regulates B Cell and T Helper Cell Subsets In Vivo and Ameliorates Collagen-Induced Arthritis	Zhu, Weiwei; Sun, Xiaolin; Zhu, Lei; et al.	Inflammation	39
2016	A Comparison of Biological Activity of B Lymphocyte Stimulator (BLyS) Antagonist Peptibodies and the Elucidation of Possible BLyS Binding Sites	Hao, Xiafei; Zhu, Yanfeng; Zheng, Chang; et al.	Protein and Peptide Letters	23
2017	Selective Binding BAFF/APRIL by the In and Outside Conservative Region of BCMA	Zheng, Chang; Zhang, Xiaojuan; Zhao, Zhen; et al.	Protein and Peptide Letters	24
2017	N6-Isopentenyladenosine promoted HeLa cell apoptosis through inhibitions of AKT and transforming growth factor beta-activated kinase 1 activation.	Li, Miao; Qi, Yonghao; Wei, Jing; et al.	Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine	39
2017	Molecular mechanism of the selectivity between BAFF/APRIL and their receptors by molecular simulations	Fu, Xuegang; Mao, Zhuo; Li, Siming; et al.	Molecular Simulation	43
2017	Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6	Qi, Yonghao; Pradipta, Ambara R.; Li, Miao; et al.	Journal of Experimental & Clinical Cancer Research	36
2017	A novel antioxidant and ACE inhibitory peptide from rice bran protein: Biochemical characterization and molecular docking study	Wang, Xiuming; Chen, Haixia; Fu, Xuegang; et al.	Lwt-Food Science and Technology	75
2011	Identification of ligand binding site on RXR gamma using molecular docking and dynamics methods	Zhao, Peng; Liao, Qing-hua; Ren, Cheng-Feng; et al.	Journal of Molecular Modeling	17
2011	Molecular docking and pharmacophore model studies of Rho kinase inhibitors	Wang, Dong-Hua; Qu, Wan-Lu; Shi, Liu-Qing; et al.	Molecular Simulation	37
30条记录,2 / 3 页 1 2 3

Jing Wei——Lecturer

Useful Links