Jiayue su——Associate Professor

Nationality:
Chinese
Phone:
15340012313
Email:
jiayuesu@tju.edu.cn
Office:
Room 314-5, Building 24
School:
School of Pharmaceutical Science and Technology
ResearcherID:
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Education Experience
2018-2022 Ph. D. biology Tsinghua University
Professional Experience
2026- Associate Professor Tianjin Univesity
2023-2024 Postdoctoral Researcher Tsinghua University
2024-2026 Postdoctoral Researcher Cambridge MRC
Research Area

We focus on using cryo-electron microscopy/electron tomography (Cryo-EM/ET) to define the molecular mechanisms of mitochondrial transport channels and the disease mechanisms underlying mitochondrial and neurodegenerative disorders.

Honors and Awards
Patents
Highlighted Publications
[1]Xuyang Tian, Jiayue Su, Ziyi Wang, Tao Liu, Huifang Xiong, Shan Sun, Kunrong Mei, Sen-Fang Sui (2025). Molecular Mechanism of PINK1 Regulation by the Hsp90 Machinery. Nat Commun. https://doi.org/10.1038/s41467-025-65859-w
[2]Jiayue Su, Xuyang Tian, Hang Cheng, Desheng Liu, Ziyi Wang, Shan Sun, Hong-Wei Wang & Sen-Fang Sui (2024). Structural insight into synergistic activation of human 3methylcrotonyl-CoA carboxylase. Nat Struct Mol Biol. doi: 10.1038/s41594-024-01379-3.
[3]Jiayue Su, Xuyang Tian, Ziyi Wang, Jiawen Yang, Shan Sun and Sen-Fang Sui (2024). Structure of the intact Tom20 receptor in the human translocase of the outer membrane complex. PNAS Nexus. 3(7): pgae269. doi:10.1093/pnasnexus/pgae269.
[4]Jiayue Su, Desheng Liu, Fan Yang, Mei-Qing Zuo, Chang Li, Meng-Qiu Dong, Shan Sun & Sen-Fang Sui (2022). Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors. PNAS, 119, e2200158119. doi: 10.1073/pnas. 2200158119.
[5]Jiao Yang, Yinong Zong, Jiayue Su, Hongtao Li, Huanyu Zhu, Linda Columbus, Lei Zhou1 & Qinglian Liu (2017). Conformation transitions of the polypeptide- binding pocket support an active substrate release from Hsp70s. Nat Commun. 8(1):1201. doi: 10.1038/s41467-017-01310-z.