Chao Li——
Nationality:
Chinese
Phone:
+86 (10)80706016
Email:
lichao@nibs.ac.cn
Office:
National Institute of Biological Sciences, Beijing, 7 Science Park Road, Life Science Park, Beijing, 102206
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
www.lichaolab.com
Education Experience
2008-2013 Ph. D. Organic Chemistry NIBS & Tianjin University
2004-2008 Bachelor Pharmaceutical Engineering Qingdao University of Science and Technology
Professional Experience
2023- Associate Investigator National Institute of Biological Sciences, Beijing
2017-2023 Assistant Investigator National Institute of Biological Sciences, Beijing
2014-2017 Postdoctoral Associate The Scripps Research Institute, La Jolla
2013-2014 Research Associate National Institute of Biological Sciences, Beijing
Research Area

Investigating potential therapeutic agents through the development of innovative chemical transformations and synthetic strategies for natural and synthetic small molecules with significant biological relevance.
Honors and Awards
2022, Wuxi AppTec Life Science and Chemistry Award
2021, Chinese Chemical Society Young Chemist Award
2020, Thieme Chemistry Journals Award
2019, National 1000-Youth Talents Program
2018, Beijing Overseas Talent Aggregation Project
2013, Carl Storm International Diversity (CSID) Fellowship for Gordon Research Conference
2012, National Scholarship for Excellence in Scientific Research
2011, NIBS Graduate Student Excellence Award
Patents
Du, N.; Shao, F.; O’yang C.; Li, C.; Wang, H.; Zhou, P.; Wang, Y.; Li, Y.; Tian, X. “Nucleoside-thiodiphosphate-heptose Compounds for Treating Conditions Associated with Alpk1 Activity” WO2022127914A1.
Baran, P. S.; Li, C.; Wang, J.; Chatterjee, A. K.; Kumar, M.; Yu, A. W.; Johnson, K. A.; Qin, T.; Shang, M. “Cu and Ni Catalyzed Decarboxylative Borylation Reaction” WO2018175173A1.
Lei, X.; He, S.; Li, C.; Dong, T. “Sesquiterpenoids” PCT/CN2014/076123. US Pat No. 9670226.
Highlighted Publications
Chen, C.; Yu, Y.; Lu, P.; Han, T.; Wang, H.*; Li, C.* “Establishing the Comprehensive Structure−Activity Relationship of the Natural Antibiotic Kibdelomycin/Amycolamicin” Angew. Chem. Int. Ed. 2024, e202415439
Cao, Z.; Sun, W.; Zhang, J.; Zhuo, J.; Yang, S.; Song, X.; Ma, Y.; Lu, P.; Han, T.; Li, C.* “Total Syntheses of (–)-Macrocalyxoformins A and B and (–)-Ludongnin C” Nat. Comm. 2024, 15, 6052.
Ying, X.; Li, Y.; Li, L.; Li, C.* “Nickel-Catalyzed C–I-Selective C(sp2)–C(sp3) Cross-Electrophile Coupling of Bromo(iodo)arenes with Alkyl Bromides” Angew. Chem. Int. Ed. 2023, 62, e202304177.
Yang, S.#; Chen, C.#; Chen, J.#; Li, C.* “Total Synthesis of the Potent and Broad-Spectrum Antibiotics Amycolamicin and Kibdelomycin” J. Am. Chem. Soc. 2021, 143, 50, 21258-21263.
Li, C.#; Wang, J.#; Barton, L. M.; Yu, S.; Tian, M.; Peters, D. S.; Kumar, M.; Yu, A. W.; Johnson, K. A.; Chatterjee, A. K.; Yan, M.; Baran, P. S.* “Decarboxylative Borylation” Science, 2017, eaam7355.
Qin, T.#; Cornella, J.#; Li, C.#; Malins, L. R.; Edwards, J. T.; Kawamura, S.; Maxwell, B. D.; Eastgate, M. D.; Baran, P. S.* “A General Alkyl-Alkyl Cross-Coupling Enabled by Redox-Active Esters and Alkylzinc Reagents” Science 2016, 352, 801-805.