Rajamanikandan——

Nationality:
Indian
Phone:
17694974324
Email:
mani.bioinfor@gmail.com
Office:
School of Pharmaceutical Science and Technology
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2012-2018 Doctor of Philosophy Bioinformatics Alagappa University
2010-2011 Master of Philosophy Bioinformatics Karpagam Academy of Higher Education
Professional Experience
2023-2024 Researcher Centre for Drug Discovery
2022-2023 Researcher Sree Balaji Medical College and Hospital
2021-2022 Researcher Alagappa University
2021-2022 Researcher NIVEDI
2017-2020 Researcher Karpagam Academy of Higher Education
Research Area

Computer Aided Drug Design

Honors and Awards
Awarded in the Summer Research Fellowship Sponsored by INSA to work at National Centre for Cell Science under the guidance of Dr. Musti. V. Krishnasastry, for two months (14th May 2018 to 8th July 2018).
Best Poster Presentation Award for the work presented in the “International Conference on Recent Advances in Modern Medicine: molecular signaling scenarios in tissues and diseases”, at Bharath University, 3rd to 4th September 2016.
Selected as Best Abstract and received a grant to present the work in the “Indo-US Workshop on Biocomputing” at National Institute of Technology, 12th -13th September 2011.
Best Poster Presentation Award for the work presented in “International conference on System Biology and Bioinformatics” at Annamalai University, 16th -17th February 2011.
Patents
Highlighted Publications
Wei Chen, Peng Cao, Yuansheng Liu, Ailing Yu, Dong Wang, Lei Chen, Rajamanikandan Sundarraj, Zhiguang Yuchi, Yong Gong, Hans Merzendorfer, Qing Yang. Structural basis for directional chitin biosynthesis. Nature
Thangaraj Sindhu, Sundaraj Rajamanikandan, Jeyaraman Jeyakanthan, Pal Debnath. Investigation of protein-ligand binding motions through protein conformational morphing and clustering of cytochrome bc1-aa3 super complex. Journal of Molecular Graphics and Modelling
Hadiatullah, H., Zhang, Y., Samurkas, A., Xie, Y., S, Rajamanikandan, Zuilhof, H., Qiao, J.*, Yuchi, Z.* Recent progress in the structural study of ion channels as insecticide targets. Insect Science
Karthika A, Balajee R, Chitra J, Prabhu D, Rajamanikandan S, Veerapandiyan M, Jeyakanthan J. Molecular dynamics simulation of toxin-antitoxin (TA) system in Acinetobacter baumannii to explore novel mechanism for inhibition of cell wall biosynthesis: zeta toxin as an effective therapeutic target. Journal of Cellular Biochemistry
Arthur S, Li Y, Hadiatullah H, Ruifang M, Yunxuan X, Rajamanikandan S, Han Z, Zhiguang Y. (2021). Ryanodine receptor as insecticide target. Current Pharmaceutical Design.
Shabir Ahmad Ganai, Srinivasan P, Rajamanikandan S, Amin Shah B, Mohan S, Gani M, Padder BA, Qadri RA, Bhat MA, Ahmad Baba Z, Ahmad Yatoo M (2021). Delineating binding potential, stability of Sulforaphane-N-acetyl-cysteine in the active site of histone deacetylase 2 and testing its cytotoxicity against distinct cancer lines through stringent molecular dynamics, DFT and cell-based assays. Chemical Biology and Drug Design
Samurkas A, Fan X, Ma D, Rajamanikandan S, Lin L, Yao L, Ma R, Jiang H, Cao P, Gao Q, Yuchi Z, (2020), Discovery of potential species-specific green insecticides targeting the Leptidopteran Ryanodine Receptor. Journal of Agriculture and Food Chemistry
Rajamanikandan S, Jeyakanthan J, Srinivasan P, (2017), Discovery of potent inhibitors targeting Vibrio harveyi LuxR through shape and e-pharmacophore based virtual screening and its biological evaluation. Microbial Pathogenesis
Rajamanikandan S, Jeyakanthan J, Srinivasan P, (2016), Molecular docking, molecular dynamics simulations, computational screening to design quorum sensing inhibitors targeting LuxP of Vibrio harveyi and its biological evaluation. Journal of Applied Biochemsitry and Biotechnology
Rajamanikandan S, Jeyakanthan J, Srinivasan P, (2016), Binding mode exploration of LuxR-thiazolidinedione analogues, e-pharmacophore based virtual screening in the designing of LuxR inhibitors and its biological evaluation. Journal of Biomolecular Structure and Dynamics