Yiling Hu——Postdoctor
Nationality:
China
Phone:
Email:
huyiling10@163.com
Office:
C401, Building 24
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
http://zhangyanlab.org/
Education Experience
2018-2023 Ph. D. Pharmacy Nanjing University
2012-2016 M.S. Microbiology Anhui University
2008-2012 Bachelor Biotechnology Anhui University
Professional Experience
2024- postdoctor Tianjin University
Research Area

Identification and characterization of new enzymes and new metabolic pathways in nature using a combination of bioinformatics, genetic, biochemical and biophysical methods. 
Honors and Awards
Patents
1. Zhang Lixin, Hu Yiling, Lou Chunbo, Bai Chaoxian, Miao Jin, Xiang Sihai, Huang Pei. A genetic recombinant bacterium and a method applied for production or overproduction products of target genes [P]. Chinese patent: CN105176899A, 2015.
2. Zhang Yan, Chen Yihua, Nanjaraj Urs A.N., Hu Yiling, Li Pengwei. Transgenic method for obtaining blue flowers by catalytic synthesis of glutamine into indigo [P]. Chinese patent: CN111788310A, 2018.
3. Zhang Yan, Zhang Lixin, Hu Yiling. A recombinant yeast with high yield of sandalwood oil and its construction method and application [P]. Chinese patent: CN111434773A, 2019.
4. Zhang Yan, Li Peishan, Tong Yang, Hu Yiling, Liu Dazhi. Xanthine amide hydrolase and its use. Chinese patent: CN113186181A, 2020.
5. Zhang Chenyu, Lei Jieqiong, Zhou Zhen, Hu Yiling. A gene component, a delivery system containing the gene component and its application [P]. Chinese patent: CN114958850A, 2022.
Highlighted Publications
1. Hu Yiling#, Yin Fang Zhou#, Shi Jing, Ma Shi Ying, Wang Zi Ru, Tan Ren Xiang, Jiao Rui Hua*, Ge Hui Ming*. P450-Modified Ribosomally Synthesized Peptides with Aromatic Cross-Links. J. Am. Chem. Soc. 2023, 145, 27325–27335.
2. Hu Yiling#, Zhang Qi#, Liu Shuang He, Sun Jia Li, Yin Fang Zhou, Wang Zi Ru, Shi Jing, Jiao Rui Hua*, Ge Hui Ming*. Building Streptomyces albus as a Chassis for Synthesis of Bacterial Terpenoids. Chem. Sci. 2023, 14, 3661–3667.
3. Li Ling Yu, Hu Yiling, Sun Jia Lin, Yu Long Bo, Shi Jing, Wang Zi Ru, Guo Zhi Kai, Zhang Bo, Guo Wen Jie, Tan Ren Xiang*, Ge Hui Ming*. Resistance and phylogeny guided discovery reveals structural novelty of tetracycline antibiotics. Chem. Sci. 2022, 13, 12892–12898.
4. Nanjaraj Urs A.N., Hu Yiling, Li Pengwei, Yuchi Zhiguang, Chen Yihua, Zhang Yan*. Cloning and Expression of a Nonribosomal Peptide Synthetase to Generate Blue Rose. ACS Synth. Biol. 2019, 8, 1698–1704.
5. Hua Gaoqun#, Hu Yiling#, Yang Chunyu, Liu Dazhi, Mao Zhuo, Zhang Lixin*, Zhang Yan*. Characterization of santalene synthases using an inorganic pyrophosphatase coupled colorimetric assay. Anal. Biochem. 2018, 547, 26–36.
6. Guo Cuixia#, Hu Yiling#, Yang Chunyu, Nanjaraj Urs AN, Zhang Yan*. Developing a colorimetric assay for Fe(II)/2-oxoglutarate-dependent dioxygenase. Anal. Biochem. 2018, 548, 109–114.
7. Xi Meng Yu#, Hu Yiling#, Gu Yu Cheng, Ge Hui Ming*. Genome mining-directed discovery for natural medicinal products. Synth. Biol. J. 2024, DOI: 10.12211/2096-8280.2023-086.
8. Bai Chaoxian#, Zhang Yang#, Zhao Xuejin#, Hu Yiling, Xiang Sihai, Miao Jin, Lou Chunbo*, Zhang Lixin*. Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products in Streptomyces. Proc. Natl. Acad. Sci. U. S. A. 2015, 112, 12181–12186.
9. Liu Shuang He, Sun Jia Li, Hu Yiling, Zhang Li, Zhang Xuan, Yan Zhang Yuan, Guo Xing, Guo Zhi Kai, Jiao Rui Hua, Zhang Bo, Tan Ren Xiang*, Ge Hui Ming*. Biosynthesis of Sordarin Revealing a Diels-Alderase for the Formation of the Norbornene Skeleton. Angew. Chem. Int. Ed. 2022, 61, e202205577.
10. Tong Yang#, Wei Yifeng#, Hu Yiling, Ang Ee Lui, Zhao Huimin*, Zhang Yan*. A Pathway for Isethionate Dissimilation in Bacillus krulwichiae. Appl. Environ. Microbiol. 2019, 85, e00793-19.