Yang Tong——Associate Professor
Nationality:
China
Phone:
13163057527
Email:
yangtong_36@tju.edu.cn
Office:
Room 417-5, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2013-2017 Bachelor Pharmaceutical Engineering Henan Normal University
2017-2019 M.S. Pharmacy Tianjin University
2019-2023 Ph. D. Applied Chemistry Tianjin University
Professional Experience
2023- Associate Professor Tianjin University
Research Area

(1) Microbial purine metabolism

(2) Sulfonate degradation pathway in Gram-positive bacteria
Honors and Awards
Patents
Zhang Y.; Zhou Y.; Tong Y.; Liu S. Preparation of isoguanine deoxyribonucleotides. China application No. 202210034330.7.
Zhang Y.; Zhou Y.; Tong Y. Enzymes involved in phage diaminopurine synthesis, and use thereof. China application No. 202110045505.X.
Zhang Y.; Li P.; Tong Y.; Hu Y.; Liu D. 4-Ureido-5-carboxyl-imidazoel-amide hydrolase and use thereof. China application No. 202010036519.0; PCT application No. PCT/CN2021/071497.
Zhang Y.; Li P.; Tong Y.; Hu Y.; Liu D. Xanthine amide hydrolase and use thereof. China application No. 202010036500.6; PCT application No. PCT/CN2021/071501.
Highlighted Publications
Tong Y.#; Wu X.#; Liu Y.#; Chen H.; Zhou Y.; Jiang L.; Li M.*; Zhao S.*; Zhang Y.*. Alternative Z-genome biosynthesis pathway shows evolutionary progression from archaea to phage. Nature Microbiology 2023, 8, 1330-1338.
Tong Y.#; Wei Y.#; Ju Y.#; Li P.; Zhang Y.; Li L.; Gao L.; Liu S.; Liu D.; Hu Y.; Li Z.; Yu H.; Luo Y.; Wang J.; Wang Y.*; Zhang Y.*. Anaerobic purinolytic enzymes enable dietary purine clearance by engineered gut bacteria. Cell Chemical Biology 2023, 30, 1-11.
Tong Y.#; Wei Y.#; Hu Y.; Ang EL.; Zhao H.*; Zhang Y.*. A pathway for isethionate dissimilation in Bacillus krulwichiae. Applied and Environmental Microbiology 2019, 85 (15), e00793-19.
Wei Y.#; Tong Y.; Zhang Y.*. New mechanisms for bacterial degradation of sulfoquinovose. Bioscience Reports 2022, 42 (10), BSR20220314.
Zhao F.#; Wei Y.#; Wang X.; Zhou Y.; Tong Y.; Ang EL.; Liu S.*; Zhao H*, Zhang Y.*. Enzymatic Synthesis of the Unnatural Nucleotide 2'-Deoxyisoguanosine 5'-Monophosphate. ChemBioChem 2022, 23 (21), e202200295.
Xing M.#; Wei Y.#; Zhou Y.; Zhang J.; Lin L.; Hu Y.; Hua G.; Nanjaraj A.N.; Liu D.; Wang F.; Guo C.; Tong Y.; Li M.; Liu Y.; Ang E. L.; Zhao H.*; Yuchi Z.*; Zhang Y.*. Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria. Nature Communication 2019, 10 (1), 1609.