Xin Li——Associate Professor
Nationality:
Phone:
Email:
lixin23@tju.edu.cn
Office:
Room 417-3, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
https://orcid.org/0000-0001-6044-6782?lang=en
Group weblink
Education Experience
2019-2022 Ph. D. Biomedical Engineering Technical University of Denmark
2015-2017 M.S. Pharmaceutical Sciences Peking University
2011-2015 Bachelor Pharmaceutics Peking University
Professional Experience
2022-2023 Postdoc Technical University of Denmark
Research Area

(1) Cancer Immunoengineering

(2) Non-viral Delivery of Nucleic Acid Drugs

(3) Live Cell Mediated Drug Delivery
Honors and Awards
Patents
Highlighted Publications
Jin, W. #, Li, X. #, Argandona, S. M., Ray, R. M., Lin, M. K. T. H., Melle, F., Clergeaud, G., Lars Andresen, T., Nielsen, M., Fairen‐Jimenez, D., Astakhova, K., & Qvortrup, K. (2025). Surface engineering of metal-organic framework nanoparticles-based miRNA carrier: Boosting RNA stability, intracellular delivery and synergistic therapy. Journal of Colloid and Interface Science, 677, 429–440. 共同一作，IF 9.4
Fan, L., Du, P., Li, Y., Chen, X., Liu, F., Liu, Y., Petrov, A. M., Li, X.*, Wang, Z.*, & Zhao, Y.* (2024). Targeted Liposomes Sensitize Plastic Melanoma to Ferroptosis via Senescence Induction and Coenzyme Depletion. ACS nano, 18(9), 7011–7023. 共同通讯，IF 15.8
Li, X., Weller, S., Clergeaud, G., & Andresen, T. L. (2024). A versatile method for conjugating lipid nanoparticles on T cells through combination of click chemistry and metabolic glycoengineering. Biotechnology journal, 19(1), e2300339. 第一作者，IF 4.4
Li, X., Halldórsdóttir, H. R., Weller, S., Colliander, A., Bak, M., Kempen, P., Clergeaud, G., & Andresen, T. L. (2022). Enhancing Adoptive Cell Therapy by T Cell Loading of SHP2 Inhibitor Nanocrystals before Infusion. ACS nano, 16(7), 10918–10930. 第一作者，IF 15.8
Li, X., Sun, A. N., Liu, Y. J., Zhang, W. J., Pang, N., Cheng, S. X., & Qi, X. R. (2018). Amphiphilic dendrimer engineered nanocarrier systems for co-delivery of siRNA and paclitaxel to matrix metalloproteinase-rich tumors for synergistic therapy. NPG Asia Materials, 10(4), 238–254. 第一作者，IF 9.6
Li, X., Halldórsdóttir, H., Weller, S., Colliander, A., Jæhger, D., Bak, M., Clergeaud, G., & Andresen, T. (2021). Exploiting T cells as vehicles of liposomal SHP2i to enhance adoptive cell therapy. Journal for ImmunoTherapy of Cancer, 9(Suppl 2), A641–A641.
Li, X., Pang, N., Li, J., & Qi, X. (2017). Characterization of amphiphilic dendrimer modified PEG-PLA nanoparticles prepared by a double emulsion-solvent evaporation method. Journal of Chinese Pharmaceutical Sciences, 26(7), 521–527.
Jin, W., Li, X., Clergeaud, G., Ray, R. M., Hong Lin, M. K. T., Andresen, T. L., Gotfredsen, C. H., Nielsen, M., Astakhova, K., & Qvortrup, K. (2022). Small RNA stabilization via non-covalent binding with a metalloporphyrin nanocage to accomplish synergistic gene and photodynamic therapy. Cell Reports Physical Science, 3(12).
Weller, S., Li, X., Petersen, L. R., Kempen, P., Clergeaud, G., & Andresen, T. L. (2024). Influence of different conjugation methods for activating antibodies on polymeric nanoparticles: Effects for polyclonal expansion of human CD8+ T cells. International immunopharmacology, 129, 111643.
Grier KE, Hansen AH, Haxvig CS, Li X, Krigslund O, Behrendt N, Engelholm LH, Rossi F, Sousa BC, Harradence GJ, Camper N, Qvortrup KM. Targeted delivery of alcohol-containing payloads with antibody-drug conjugates. Chem Commun (Camb). 2023 Jun 8;59(47):7240-724
Su HT, Li X, Liang DS, Qi XR. Synthetic low-density lipoprotein (sLDL) selectively delivers paclitaxel to tumor with low systemic toxicity. Oncotarget. 2016; 7: 51535-51552.