Jianhui Huang——Professor

Nationality:
CHINA
Phone:
022-27409894
Email:
jhuang@tju.edu.cn
Office:
Office 514C, Building 24, Tianjin University
School:
School of Pharmaceutical Science and Technology
ResearcherID:
Group weblink
Education Experience
2003-2006 Doctor of Philosophy  Chemistry University of York, UK
1996-2000 Bachelor of Science Chemistry Hu'nan University
Professional Experience
2007-2010 Postdoctorial Research Associate University of Sheffield and GlaxoSmithKlein
2010-2023 Associate Professor/Professor Tianjin University, China
Research Area

The research of the Huang group encompasses the following main areas:  


1) Molecular design (AIDD & Chiral Catalyst/ligand Design)



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2) XDC Drug Development and Preparation (Protac/RDC...)



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3) New Chemical Space Exploration



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Honors and Awards
Teaching Award, HSP, Tianjin University, 2018
Thieme Chemistry Journal Award, 2017
Best Publication Award, HSP, Tianjin University, 2015
Patents
黄剑辉; 刘柳; 曾凡云; 陈晨; 李一凡 ; 手性二胺类化合物和应用以及亚胺的不对称加成方法, 2021-04-14, 中国, ZL202110401309.1 (专利)
钌催化下的2-(3-溴苯基)吡啶类衍生物的合成, 2015031900635430, 黄剑辉、于庆贞、胡乐安、王悦、赵康, 2016.09
3-羟基-2-烷氧基-3-苯基异吲哚-1(2H)-酮类衍生物的制备方法, 2013102117068, 黄剑辉、刘伟东、朱怡、于庆贞、张娜娜, 2015.07
Highlighted Publications
Qing Wang,† Fanhao Meng,† Yuting Xie, Wei Wang, Yumin Meng, Linjie Li, Tao Liu, Jianxun Qi, Xiaodan Ni, Sanduo Zheng, Jianhui Huang,* Niu Huang.* In Silico Discovery of Small Molecule Modulators Targeting the Achilles' Heel of SARS-CoV- 2 Spike Protein. ACS Cent. Sci. 2023. 9, 252–265. doi: 10.1021/acscentsci.2c01190.
Xiaoli Qin, Lin Huang, Ziying Zhan, Peng Fu, Congyang Zhang, Jianhui Huang, Zhifeng Ding.“Enhancing corannulene electrochemiluminescence and chemiluminescence by means of an Azabora-helicene to slow down its bowl inversion.” Chem. Sci., 2024, accepted.
Lin Huang, Qing Wang, Peng Fu, Yuzhu Sun, Duncan Browne, Jianhui Huang. “Extended Quinolizinium-Fused Corannulene Derivatives: Synthesis and Properties.”JACS Au (An Open Access Journal of The American Chemical Society), 2024, 4, 1623-1631.
Lin Huang. Mengyu Qiu, Zhihao Chang, Duncan Browne, Jianhui Huang.“C–H Activation Enabled Piperazine-Embedded Azadibenzo[a,g]corannulene Synthesis.”Org. Chem. Front., 2024, 11, 2807-2814.
Q. Yu; L. Hu; Y. Wang; S. Zheng; J. Huang "Directed meta-selective bromination of arenes with ruthenium catalysts." Angew. Chem. Int. Ed., 2015, 54, 15284-15288.